Compilation of free information about human parts, their function, assembly, repair, and maintenance
Glycosome
The glycosome is a membrane-enclosed organelle that contains the glycolytic enzymes. It is found in a few species of protozoa, most notably in the human pathogenic trypanosomes, which can cause sleeping sickness and Chagas's disease, and Leishmania. The organelle is bounded by a single membrane and contains a dense proteinaceous matrix. It is believed to have evolved from the peroxisome.[1] This has been verified by work done on Leishmania genetics. [2]
The glycosome is currently being researched as a possible target for drug therapies.
[edit] References
- ^ Parsons M (2004). "Glycosomes: parasites and the divergence of peroxisomal purpose". Mol Microbiol 53 (3): 717–24. doi:. PMID 15255886.
- ^ Flaspohler, J.A., W.L. Rickoll, S.M. Beverley, and M. Parsons. 1997. Functional identification of a Leishmania gene related to peroxin 2 reveals common ancestry of glycosomes and peroxisomes. Mol. Cell. Biol. 17(3):1093-1101.
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The content of this section is licensed under the GNU Free Documentation License (local copy). It uses material from the Wikipedia article "Glycosome" modified November 23, 2009 with previous authors listed in its history.
