Lipotropin

Lipotropin is a hormone produced by the cleavage of pro-opiomelanocortin (POMC). The anterior pituitary gland produces the pro-hormone POMC, which undergoes cleavage to adrenocorticotropin (ACTH) and β-lipotropin (β-LPH).

Beta-lipotropin

β-lipotropin is a 90 amino acid polypeptide that is the carboxy-terminal fragment of POMC.

It stimulates melanocytes to produce melanin, and can also be cleaved into smaller peptides. In humans, γ-lipotropin, α-MSH, β-MSH, γ-MSH, α-endorphin, β-endorphin, γ-endorphin, and met-enkephalin are all possible fragments of β-lipotropin.^[1]

β-lipotropin also performs lipid-mobilizing functions such as lipolysis and steroidogenesis.

Gamma-lipotropin

γ-lipotropin is the amino-terminal peptide fragment of β-lipotropin. In humans, it has 56 amino acids.

External links

• MeSH beta-Lipotropin
• MeSH gamma-Lipotropin

References